EBOO — Extracorporeal Blood Oxygenation and Ozonation — circulates your blood through a closed, sterile filtration system outside the body, where it is exposed to a controlled mix of oxygen and medical ozone before being returned to you. Because it processes a larger volume than small-sample ozone methods, a single session works through several liters of blood over roughly 45–60 minutes.
At Harper MD in Weston, FL, EBOO is performed under medical oversight and offered only after an evaluation confirms it’s appropriate for you — as a complement to your broader care, never a replacement for proven medical treatment.
EBOO uses two intravenous lines — one that draws blood into a closed, single-use circuit, and one that returns it. As the blood circulates through the system, it passes through a medical-grade filter and is exposed to a controlled mixture of oxygen and ozone under sterile conditions, then flows back into your body. The circuit runs continuously, which is what allows a session to process several liters rather than a small sample.
Medical ozone is a controlled mixture of oxygen and ozone gas. Ozone is highly reactive, so dosing and equipment matter: this is a procedure for a clinical setting with trained staff, not a wellness add-on. For an independent, plain-language overview of ozone therapy and where the evidence currently stands, the Cleveland Clinic’s overview is a useful reference.
Book My Free EvaluationBefore anything else, we review your health history, medications, and goals — and screen for the conditions that make EBOO inappropriate. If it isn’t right for you, we’ll tell you.
You recline comfortably with an IV line in each arm while your blood circulates through the closed system. Most people rest, read, or relax. A session generally takes about 45–60 minutes and is typically painless aside from the IV placement.
Most people resume normal activities the same day, though some prefer to rest and hydrate. Mild, temporary effects can occur and are discussed with you in advance. Any plan is built as a series and adjusted over time, with your response monitored throughout.
Patients explore EBOO for a range of wellness and recovery goals. The items below describe areas EBOO is commonly associated with — not guaranteed outcomes.
Supports the body’s natural filtration and circulation
May help regulate inflammation
Associated with cellular and mitochondrial performance
May support oxygen delivery to tissues
Explored for energy and recovery support
Explored for immune resilience support
Individual responses vary. EBOO is not a treatment for any specific disease and is offered only when appropriate for you.
Because EBOO involves circulating your blood and exposing it to a reactive gas, candidate screening is not optional — it is the most important part of the process. Here is what that means.
Screening exists to catch these before you ever begin.
Most effects are mild and short-lived. Your provider reviews these with you before you begin, along with how to prepare and recover.
EBOO is not a treatment for any specific disease, and we won’t present it as one. It is offered as an adjunct within a broader, individualized plan — never as a replacement for proven medical care. If EBOO isn’t appropriate for you, or if another approach fits your situation better, we’ll say so plainly. See the regulatory note at the bottom of this page.
EBOO is a self-pay service at Harper MD. That doesn’t mean it has to come entirely out of pocket — most patients use one of the following, and we’ll help you figure out which fits your situation.
Many patients are able to use Health Savings Account (HSA) or Flexible Spending Account (FSA) funds toward EBOO, sometimes with a letter of medical necessity from your provider — which we can help you obtain when appropriate.
Eligibility rules are set by the IRS and your plan, so confirm the specifics with your plan administrator.
Prefer to spread the cost over time? Harper MD offers financing through Cherry and CareCredit, so you can begin a planned course without paying the full amount up front.
See options and apply on our Payment Plans page, or ask us to walk you through them during your evaluation.
This information is provided as a general starting point and is not tax, legal, insurance, or financial advice. Coverage and eligibility depend on your individual plan — confirm details with your plan administrator or tax advisor.
Straight answers to what patients ask most. If yours isn’t here, our team is glad to answer it directly.
No. The U.S. Food and Drug Administration has not approved ozone therapy for any medical condition, and considers medical ozone an area where evidence remains limited. We share that plainly rather than around it. EBOO is offered at Harper MD as an elective, adjunctive wellness procedure — not as an approved treatment for any disease — and only when an evaluation confirms it’s appropriate for you. See the regulatory note at the bottom of this page.
You recline comfortably with an IV line in each arm while your blood circulates through the closed system. Most people find it calm — they rest, read, or relax. A session generally runs about 45–60 minutes and is typically painless apart from the IV placement.
EBOO is generally not appropriate during pregnancy or breastfeeding, or for people with G6PD deficiency, active bleeding disorders, or severe cardiovascular instability. Some other conditions — such as a recent heart attack, severe anemia, or uncontrolled hyperthyroidism — may require special evaluation first. This is exactly why every candidate is screened before beginning.
There is no single answer — it depends on your goals and what your evaluation shows. EBOO is generally approached as a planned series rather than a one-time visit, and the number and spacing of sessions are set during your evaluation and adjusted over time.
We view EBOO as one elective option within a broader, individualized plan — not a standalone fix. Everything begins with a free evaluation, where we look at the whole picture before recommending anything. Explore our full range of therapy modalities or services to see how the pieces fit together.
The statements on this page have not been evaluated by the U.S. Food and Drug Administration. The FDA has not approved ozone therapy, including EBOO, for the diagnosis, treatment, cure, or prevention of any disease. EBOO is offered at Harper MD as an elective, adjunctive wellness procedure and is not a substitute for diagnosis, treatment, or advice from a qualified licensed medical provider.
Individual results vary. Any decision to pursue EBOO should be made in consultation with your Harper MD provider after an individual evaluation. If you are experiencing a medical emergency, call 911.
Your first evaluation at Harper MD is free, unhurried, and carries no commitment. We’ll review your goals and history, screen for suitability, and tell you plainly whether EBOO is a sensible fit for you.
17150 Royal Palm Blvd #3, Weston, FL · Serving West Broward & Greater South Florida